| # | Player | Sixes | Innings |
|---|---|---|---|
| 1 | ST Jayasuriya | 31 | 514 runs |
| 2 | SE Marsh | 26 | 616 runs |
| 3 | YK Pathan | 25 | 435 runs |
| 4 | V Sehwag | 21 | 406 runs |
| 5 | Yuvraj Singh | 19 | 299 runs |
| 6 | SR Watson | 19 | 472 runs |
| 7 | AC Gilchrist | 19 | 436 runs |
| 8 | RG Sharma | 19 | 404 runs |
| 9 | SK Raina | 18 | 421 runs |
| 10 | DJ Hussey | 17 | 319 runs |
| 11 | SC Ganguly | 15 | 349 runs |
| 12 | BB McCullum | 15 | 188 runs |
| 13 | MS Dhoni | 15 | 414 runs |
| 14 | Y Venugopal Rao | 15 | 288 runs |
| 15 | JA Morkel | 14 | 241 runs |
| 16 | R Dravid | 11 | 371 runs |
| 17 | MEK Hussey | 11 | 168 runs |
| 18 | LRPL Taylor | 10 | 149 runs |
| 19 | AM Nayar | 9 | 206 runs |
| 20 | RV Uthappa | 9 | 320 runs |
